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AOD-9604 stands for “Anti-Obesity Drug 9604.”
It’s a synthetic fragment of human growth hormone (hGH), specifically amino acids 176–191.
Designed to retain the fat-metabolizing effects of hGH while avoiding unwanted growth-promoting actions (like increased IGF-1).
Stimulates lipolysis → enhances the breakdown of stored fat.
Inhibits lipogenesis → reduces new fat formation.
Works primarily on adipose tissue (fat cells) without significantly affecting blood sugar or growth factors.
Animal studies: Showed reduced body fat and improved lipid metabolism.
Human trials:
Found it to be safe and well tolerated.
Fat-loss results were modest and inconsistent, which is why it was never FDA-approved as a prescription weight-loss drug.
In 2013, the Australian TGA approved it as a cosmetic ingredient, but not as a medicine.
Generally considered safe in studies.
Side effects are uncommon but may include: mild headache, nausea, or local injection site irritation.
Does not increase IGF-1 → lower risk of unwanted tissue growth compared to hGH.
Long-term safety data in humans is still limited.
AOD-9604 = hGH fragment (176–191) aimed at fat reduction.
Mechanism: Encourages fat breakdown and prevents new fat storage.
Dosing (research use): 250–500 mcg subQ daily, 8–12 weeks.
Evidence: Safe, but only modest fat-loss results in human trials.
Status: Not FDA-approved; used experimentally in wellness/weight-management clinics.
AOD-9604 stands for “Anti-Obesity Drug 9604.”
It’s a synthetic fragment of human growth hormone (hGH), specifically amino acids 176–191.
Designed to retain the fat-metabolizing effects of hGH while avoiding unwanted growth-promoting actions (like increased IGF-1).
Stimulates lipolysis → enhances the breakdown of stored fat.
Inhibits lipogenesis → reduces new fat formation.
Works primarily on adipose tissue (fat cells) without significantly affecting blood sugar or growth factors.
Animal studies: Showed reduced body fat and improved lipid metabolism.
Human trials:
Found it to be safe and well tolerated.
Fat-loss results were modest and inconsistent, which is why it was never FDA-approved as a prescription weight-loss drug.
In 2013, the Australian TGA approved it as a cosmetic ingredient, but not as a medicine.
Generally considered safe in studies.
Side effects are uncommon but may include: mild headache, nausea, or local injection site irritation.
Does not increase IGF-1 → lower risk of unwanted tissue growth compared to hGH.
Long-term safety data in humans is still limited.
AOD-9604 = hGH fragment (176–191) aimed at fat reduction.
Mechanism: Encourages fat breakdown and prevents new fat storage.
Dosing (research use): 250–500 mcg subQ daily, 8–12 weeks.
Evidence: Safe, but only modest fat-loss results in human trials.
Status: Not FDA-approved; used experimentally in wellness/weight-management clinics.