DSIP 5mg

$25.00
  • DSIP is a naturally occurring neuropeptide first isolated in 1977 from rabbit brains.

  • It’s composed of 9 amino acids (a nonapeptide) and found in various brain regions, blood plasma, and peripheral organs.

  • Its name comes from its original discovery: it was thought to promote delta-wave sleep (deep sleep).

  • Available today mostly through compounding or research supply, since it’s not FDA-approved as a medication.

⚙️ Mechanisms of Action (Proposed)

Research suggests DSIP has multiple neuromodulatory roles, though its exact mechanism is still not fully understood:

  • Sleep regulation → May promote delta-wave activity, deeper restorative sleep, and circadian rhythm balance.

  • Endocrine modulation → Influences secretion of LH (luteinizing hormone), ACTH, and may regulate cortisol and melatonin cycles.

  • Neuroprotection → Reduces oxidative stress and stabilizes neuronal membranes.

  • Pain & stress response → May act on opioid peptide systems and modulate stress-related hormones.

  • Immune support → Shows some immunomodulatory effects in preclinical models.

📌 Potential Benefits (Research/Clinic Settings)

  • Improved sleep quality (deep sleep, fewer nighttime awakenings)

  • Reduced stress & anxiety

  • Better hormone balance (especially cortisol and growth hormone regulation)

  • Neuroprotection (studied in epilepsy, neurodegeneration, oxidative stress)

  • Pain management (linked to endorphin pathways)

  • Jet lag & circadian rhythm support

👉 Evidence is mixed—some studies show benefits, others inconclusive.

⚠️ Safety & Side Effects

  • Generally reported as well tolerated.

  • Side effects: mild fatigue, headache, vivid dreams, or slight dizziness in some individuals.

  • Long-term safety data is lacking.

  • Not recommended in pregnant or breastfeeding women, or in those with severe endocrine disorders, unless supervised by a physician.

✅ Key Takeaways

  • DSIP = 9-amino acid peptide studied for its role in sleep regulation, stress reduction, and neuroprotection.

  • Dosing: usually 100–500 mcg subQ before bedtime, from a 10 mg vial.

  • Evidence: Some promising results for sleep and stress, but research is limited and not conclusive.

  • Status: Experimental, not FDA-approved, available mainly as a research peptide.

  • DSIP is a naturally occurring neuropeptide first isolated in 1977 from rabbit brains.

  • It’s composed of 9 amino acids (a nonapeptide) and found in various brain regions, blood plasma, and peripheral organs.

  • Its name comes from its original discovery: it was thought to promote delta-wave sleep (deep sleep).

  • Available today mostly through compounding or research supply, since it’s not FDA-approved as a medication.

⚙️ Mechanisms of Action (Proposed)

Research suggests DSIP has multiple neuromodulatory roles, though its exact mechanism is still not fully understood:

  • Sleep regulation → May promote delta-wave activity, deeper restorative sleep, and circadian rhythm balance.

  • Endocrine modulation → Influences secretion of LH (luteinizing hormone), ACTH, and may regulate cortisol and melatonin cycles.

  • Neuroprotection → Reduces oxidative stress and stabilizes neuronal membranes.

  • Pain & stress response → May act on opioid peptide systems and modulate stress-related hormones.

  • Immune support → Shows some immunomodulatory effects in preclinical models.

📌 Potential Benefits (Research/Clinic Settings)

  • Improved sleep quality (deep sleep, fewer nighttime awakenings)

  • Reduced stress & anxiety

  • Better hormone balance (especially cortisol and growth hormone regulation)

  • Neuroprotection (studied in epilepsy, neurodegeneration, oxidative stress)

  • Pain management (linked to endorphin pathways)

  • Jet lag & circadian rhythm support

👉 Evidence is mixed—some studies show benefits, others inconclusive.

⚠️ Safety & Side Effects

  • Generally reported as well tolerated.

  • Side effects: mild fatigue, headache, vivid dreams, or slight dizziness in some individuals.

  • Long-term safety data is lacking.

  • Not recommended in pregnant or breastfeeding women, or in those with severe endocrine disorders, unless supervised by a physician.

✅ Key Takeaways

  • DSIP = 9-amino acid peptide studied for its role in sleep regulation, stress reduction, and neuroprotection.

  • Dosing: usually 100–500 mcg subQ before bedtime, from a 10 mg vial.

  • Evidence: Some promising results for sleep and stress, but research is limited and not conclusive.

  • Status: Experimental, not FDA-approved, available mainly as a research peptide.