Ipamorelin 10mg

🔬 What Is Ipamorelin?

• Ipamorelin is a synthetic pentapeptide that acts as a ghrelin mimetic (Growth Hormone Secretagogue).

• It binds to the ghrelin receptor (GHS-R1a) on pituitary cells, stimulating the release of growth hormone (GH).

• Considered one of the “cleanest” GH secretagogues, because it does not significantly raise cortisol or prolactin (unlike older peptides like GHRP-6 or GHRP-2).

⚙️ Mechanism of Action

• Mimics ghrelin → signals the pituitary to release GH.

• Works best when combined with a GHRH analog (like CJC-1295 or Sermorelin) for a stronger, synergistic GH pulse.

• Effects:

  • Increased GH → higher IGF-1 levels

  • Stimulates lipolysis (fat breakdown)

  • Supports muscle repair, recovery, and growth

  • Enhances deep sleep quality

📊 Reported Benefits

• Body composition: Increased lean muscle mass, decreased body fat

• Recovery: Faster healing and exercise recovery

• Sleep: Improved deep sleep, leading to better recovery and energy

• Skin/joint support: Collagen stimulation → improved skin elasticity, joint repair

• Anti-aging: Supports youthful GH and IGF-1 levels as they naturally decline with age

⚠️ Safety & Side Effects

• Generally considered very well tolerated.

• Reported side effects (rare, usually mild):

  • Headache

  • Flushing or dizziness

  • Slight water retention or numbness/tingling in extremities (signs of GH elevation)

• Low risk of increasing cortisol, prolactin, or appetite compared to older GHRPs.

✅ Key Takeaways

• Ipamorelin = ghrelin mimetic / GH secretagogue.

• Dose: 200–300 mcg SC, once or twice daily.

• Best used with a GHRH analog (like CJC-1295 or Sermorelin) for stronger effect.

• Benefits: fat loss, muscle gain, recovery, better sleep, anti-aging.

• Side effects: minimal compared to older peptides, generally safe when monitored.