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KPV is a tripeptide fragment (Lys-Pro-Val) derived from the hormone α-MSH (alpha-melanocyte-stimulating hormone).
Unlike the full α-MSH peptide, KPV is non-pigmenting (it doesn’t darken the skin), but it keeps many of α-MSH’s anti-inflammatory and healing properties.
Naturally present in the body, but also produced synthetically for research and clinical use.
Anti-inflammatory: Inhibits pro-inflammatory cytokines (like TNF-α, IL-1, IL-6).
Gut health: Shown to reduce colitis and intestinal inflammation in animal studies.
Skin protection: Protects against UV damage and promotes wound healing.
Antimicrobial activity: Mild ability to fight certain bacteria.
Immune modulation: Helps regulate excessive immune response without full immunosuppression.
Gut inflammation: Studied for IBD (Crohn’s disease, ulcerative colitis), IBS, and leaky gut.
Skin health: Used in creams/lotions for eczema, psoriasis, and wound healing.
Systemic inflammation: May support recovery from chronic inflammatory conditions.
Post-injury/tissue repair: Supports healing and reduces swelling.
Considered very safe; well tolerated in studies.
Non-pigmenting (unlike other melanocortin peptides).
Rare mild side effects: injection site redness, stomach upset (oral use).
Long-term safety in humans still being studied.
KPV = anti-inflammatory tripeptide derived from α-MSH.
Benefits: gut healing, reduced inflammation, improved skin health, wound repair.
Forms: oral, injectable, topical, suppository.
Status: Experimental but promising; safe profile compared to many other peptides.
KPV is a tripeptide fragment (Lys-Pro-Val) derived from the hormone α-MSH (alpha-melanocyte-stimulating hormone).
Unlike the full α-MSH peptide, KPV is non-pigmenting (it doesn’t darken the skin), but it keeps many of α-MSH’s anti-inflammatory and healing properties.
Naturally present in the body, but also produced synthetically for research and clinical use.
Anti-inflammatory: Inhibits pro-inflammatory cytokines (like TNF-α, IL-1, IL-6).
Gut health: Shown to reduce colitis and intestinal inflammation in animal studies.
Skin protection: Protects against UV damage and promotes wound healing.
Antimicrobial activity: Mild ability to fight certain bacteria.
Immune modulation: Helps regulate excessive immune response without full immunosuppression.
Gut inflammation: Studied for IBD (Crohn’s disease, ulcerative colitis), IBS, and leaky gut.
Skin health: Used in creams/lotions for eczema, psoriasis, and wound healing.
Systemic inflammation: May support recovery from chronic inflammatory conditions.
Post-injury/tissue repair: Supports healing and reduces swelling.
Considered very safe; well tolerated in studies.
Non-pigmenting (unlike other melanocortin peptides).
Rare mild side effects: injection site redness, stomach upset (oral use).
Long-term safety in humans still being studied.
KPV = anti-inflammatory tripeptide derived from α-MSH.
Benefits: gut healing, reduced inflammation, improved skin health, wound repair.
Forms: oral, injectable, topical, suppository.
Status: Experimental but promising; safe profile compared to many other peptides.