


M-2 Melanotan 10mg
π¬ What Is Melanotan II?
Melanotan II (MT-II or M-2) is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (Ξ±-MSH).
Originally developed to promote tanning by stimulating melanocortin receptors in the skin.
Unlike natural Ξ±-MSH, MT-II is much longer-lasting in the body.
βοΈ Mechanism of Action
Binds to melanocortin receptors (MC1R, MC3R, MC4R, MC5R):
MC1R β stimulates melanin production β tanning & UV protection.
MC3R / MC4R β regulates sexual arousal and appetite.
MC5R β possible role in sebaceous glands and immune function.
π Reported Effects
Skin tanning β increases melanin (can darken moles and freckles too).
Erectile function & libido β one of the most notable βside effectsβ; it directly stimulates sexual arousal (basis for development of PT-141, which is derived from MT-II).
Appetite suppression β some users report reduced hunger.
Photoprotection β may reduce sunburn risk.
β οΈ Side Effects
Nausea, flushing, facial warmth (common during loading).
Increased libido, spontaneous erections (sometimes very strong).
Darkening of moles and freckles β may complicate skin cancer screening.
Hyperpigmentation in unintended areas.
Rare: high blood pressure, fatigue, or appetite changes.
Serious caution: Since it affects melanocytes, there are concerns it could theoretically accelerate melanoma (though clinical data is limited).
β Key Takeaways
Melanotan II = synthetic Ξ±-MSH analog, promotes tanning and sexual arousal.
Dosing (research use): 100β250 mcg to start, titrating to 0.5β1 mg/day, then weekly maintenance.
Effects: tanning, increased libido, appetite suppression.
Side effects: nausea, mole darkening, hyperpigmentation, possible melanoma risk.
Status: Not FDA-approved; available only as a research chemical.
π¬ What Is Melanotan II?
Melanotan II (MT-II or M-2) is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (Ξ±-MSH).
Originally developed to promote tanning by stimulating melanocortin receptors in the skin.
Unlike natural Ξ±-MSH, MT-II is much longer-lasting in the body.
βοΈ Mechanism of Action
Binds to melanocortin receptors (MC1R, MC3R, MC4R, MC5R):
MC1R β stimulates melanin production β tanning & UV protection.
MC3R / MC4R β regulates sexual arousal and appetite.
MC5R β possible role in sebaceous glands and immune function.
π Reported Effects
Skin tanning β increases melanin (can darken moles and freckles too).
Erectile function & libido β one of the most notable βside effectsβ; it directly stimulates sexual arousal (basis for development of PT-141, which is derived from MT-II).
Appetite suppression β some users report reduced hunger.
Photoprotection β may reduce sunburn risk.
β οΈ Side Effects
Nausea, flushing, facial warmth (common during loading).
Increased libido, spontaneous erections (sometimes very strong).
Darkening of moles and freckles β may complicate skin cancer screening.
Hyperpigmentation in unintended areas.
Rare: high blood pressure, fatigue, or appetite changes.
Serious caution: Since it affects melanocytes, there are concerns it could theoretically accelerate melanoma (though clinical data is limited).
β Key Takeaways
Melanotan II = synthetic Ξ±-MSH analog, promotes tanning and sexual arousal.
Dosing (research use): 100β250 mcg to start, titrating to 0.5β1 mg/day, then weekly maintenance.
Effects: tanning, increased libido, appetite suppression.
Side effects: nausea, mole darkening, hyperpigmentation, possible melanoma risk.
Status: Not FDA-approved; available only as a research chemical.