Sermorelin 10mg

🔬 What Is Sermorelin?

• Sermorelin is a synthetic analog of Growth Hormone-Releasing Hormone (GHRH 1–29), the active fragment of natural GHRH.

• It stimulates the pituitary gland to release growth hormone (GH), which in turn boosts IGF-1 production in the liver.

• Unlike synthetic GH (somatropin), sermorelin does not replace GH directly—it encourages your body to produce it naturally.

📌 Clinical Uses

• Originally FDA-approved for diagnosing GH deficiency in children, but later withdrawn from the market for business—not safety—reasons.

• In modern clinics, it’s widely used off-label for:

  • Age-related GH decline

  • Fat loss & improved body composition

  • Sleep quality

  • Exercise recovery & performance

  • Skin, hair, and joint health

⚙️ Mechanism of Action

• Stimulates pulsatile release of GH (more physiologic than direct GH injections).

• Leads to:

  • Increased IGF-1

  • Enhanced protein synthesis & recovery

  • Improved lipolysis (fat breakdown)

  • Better deep sleep

  • Possible immune support

⚠️ Safety & Side Effects

• Generally well tolerated

• Possible side effects:

  • Injection site irritation

  • Flushing, dizziness, headache

  • Transient water retention or carpal tunnel–like symptoms (if GH levels rise too high)

• Less risk of acromegaly or GH overexposure compared to direct HGH therapy, since sermorelin relies on the body’s own feedback loops.

✅ Key Takeaways

• Sermorelin = GHRH analog that stimulates natural GH release.

• Uses: age-related GH decline, body composition, recovery, sleep, skin, and energy.

• Dose: typically 200–500 mcg SC at bedtime.

• Benefits: More physiologic than HGH, with lower risk of excess hormone exposure.

• Status: Compounded peptide, used off-label in wellness/age management clinics.