Important Safety Reminder

• Do not take GLP medications if you are already using any diabetic or blood sugar–stabilizing medications, unless specifically directed by your healthcare provider. Combining therapies without medical supervision can be dangerous.

• As with any peptide therapy, always consult your physician first to ensure you are an appropriate candidate and that the treatment is safe for your individual health needs.

Please take the time to thoroughly research any products before use. While we strive to provide comprehensive information on our website, your health and safety are ultimately your responsibility. Educating yourself about the products you plan to use allows you to form realistic expectations and better evaluate their effects.

GLP medications have rapidly gained popularity for their ability to promote weight loss and support healthier blood sugar levels.

However, it’s important to recognize that, like all therapies, they may also carry potential side effects that should be carefully considered.

What to Know Before Starting a GLP Medication

When beginning GLP therapy, it’s important to pay close attention to your body’s daily routines — especially input and output.

Hydration is critical. Adequate water intake not only supports overall health but also plays a key role in safe and effective weight loss. Aim for approximately 100 ounces of fluids per day, with water being the preferred choice since it nourishes and supports your body’s natural processes. A practical guideline is:

• Morning: at least 32 oz

• Afternoon: at least 32 oz

• Evening: at least 32 oz

Why hydration matters: Insufficient fluid intake can increase the risk of gallbladder issues, gallstones, and pancreatitis, and it may also slow or stall your weight loss progress.

Possible Side Effects of GLP Therapy

When taking GLP medications such as Semaglutide (GLP-1), Tirzepatide (GLP-2), or the newer Retatrutide (GLP-3), some individuals may experience digestive side effects.

Diarrhea

• It’s common to notice increased bowel activity when starting treatment.

• This usually resolves within a few days.

• If you experience persistent stomach cramping, your dose may be too high — consult your provider for guidance.

Constipation

• GLP medications slow digestion and decrease appetite, which may also reduce bowel movements.

• Monitor your normal routine closely. If you go more than two days beyond your usual schedule or notice hard, difficult stools, consider natural support options such as:

  • Magnesium supplements (for example, magnesium citrate blends available online).

  • Adding chia seeds to your diet (mix into yogurt, oatmeal, or baked goods). Their fiber content can help create softer, fuller stools and support regularity.

• Adequate daily hydration is essential — insufficient water intake is a major contributor to constipation on GLP therapy.

While GLP medications can have additional side effects, diarrhea and constipation are the two most common concerns. In our experience, managing these effectively early on often helps minimize or prevent many of the other potential issues.